Table 1.
Comparison of demographic and baseline clinical variables based on OCT1 genetic variant
| Variable | Genotypes | |||
|---|---|---|---|---|
| rs1867351 | C/C | C/T | T/T | P-value |
| Men | 21 (53.8) | 28 (50.0) | 20 (47.6) | 0.86 |
| Women | 18 (46.2) | 28 (50.0) | 22 (52.4) | |
| Age (y) | 55.6 ± 8.90 | 56.9 ± 12.7 | 55.2 ± 12.3 | 0.76 |
| BMI (kg/m2) | 25.6 ± 3.02 | 25.9 ± 4.05 | 25.7 ± 4.28 | 0.92 |
| Systolic BP (mmHg) | 130.6 ± 11.62 | 127.9 ± 10.54 | 132.6 ± 11.82 | 0.12 |
| Diastolic BP (mmHg) | 80.8 ± 7.44 | 78.4 ± 6.43 | 80.6 ± 7.34 | 0.57 |
| rs4709400 | C/C | C/G | G/G | P-value |
| Men | 13 (44.8) | 30 (52.6) | 26 (51.0) | 0.79 |
| Women | 16 (55.2) | 27 (47.4) | 25 (49.0) | |
| Age (y) | 55.2 ± 13.2 | 56.5 ± 12.5 | 55.9 ± 9.37 | 0.89 |
| BMI (kg/m2) | 25.8 ± 4.81 | 25.9 ± 3.92 | 25.6 ± 3.14 | 0.91 |
| Systolic BP (mmHg) | 131.7 ± 12.52 | 129.0 ± 11.91 | 130.4 ± 10.05 | 0.58 |
| Diastolic BP (mmHg) | 79.9 ± 6.64 | 79.7 ± 7.42 | 79.8 ± 7.00 | 0.99 |
| rs628031 | A/A | A/G | G/G | P-value |
| Men | 6 (66.7) | 26 (44.1) | 37 (53.6) | 0.34 |
| Women | 3 (33.3) | 33 (55.9) | 32 (46.4) | |
| Age (y) | 56.0 ± 8.54 | 55.9 ± 13.3 | 56.1 ± 10.3 | 0.99 |
| BMI (kg/m2) | 25.9 ± 3.46 | 26.1 ± 4.33 | 25.5 ± 3.45 | 0.66 |
| Systolic BP (mmHg) | 134.1 ± 12.13 | 130.3 ± 12.71 | 129.4 ± 9.99 | 0.50 |
| Diastolic BP (mmHg) | 81.89 ± 4.91 | 79.17 ± 7.41 | 79.99 ± 6.99 | 0.52 |
| rs2297374 | C/C | C/T | T/T | P-value |
| Men | 40 (53.3) | 22 (46.8) | 7 (46.7) | 0.80 |
| Women | 35 (46.7) | 25 (53.2) | 8 (53.3) | |
| Age (y) | 55.6 ± 10.9 | 57.5 ± 12.6 | 53.5 ± 11.4 | 0.46 |
| BMI (kg/m2) | 25.5 ± 3.27 | 26.4 ± 4.39 | 24.8 ± 4.59 | 0.32 |
| Systolic BP (mmHg) | 130.6 ± 11.33 | 130.1 ± 11.85 | 127.5 ± 10.13 | 0.62 |
| Diastolic BP (mmHg) | 79.81 ± 6.700 | 80.00 ± 8.280 | 78.73 ± 4.480 | 0.83 |