Table 2.
Genotype distribution and allele frequencies of rs599839 and rs464218 and rs6698843 in cases and control
| SNP | Control (%) | Case (%) | P | ||
|---|---|---|---|---|---|
|
|
|||||
| CAD | IS | CAD | IS | ||
| Rs599839 | |||||
| AA | 527 (89.3) | 511 (90.6) | 449 (85.2) | ||
| AG | 63 (10.7) | 53 (9.4) | 75 (14.2) | ||
| GG | 0 | 0 | 3 (0.6) | 0.469 | 0.034 |
| A | 1117 (94.7) | 1075 (95.3) | 973 (92.3) | ||
| G | 63 (5.3) | 53 (4.7) | 81 (7.7) | 0.481 | 0.024 |
| HWE(P) | 0.171 | 0.241 | 0.945 | ||
| Rs464218 | |||||
| AA | 207 (35.1) | 191 (33.9) | 182 (34.5) | ||
| AG | 276 (46.8) | 282 (50) | 91 (50.1) | ||
| GG | 107 (18.1) | 264 (16.1) | 81 (15.4) | 0.493 | 0.383 |
| A | 690 (58.5) | 664 (58.9) | 628 (59.6) | ||
| G | 490 (41.5) | 464 (41.1) | 426 (40.4) | 0.849 | 0.595 |
| HWE(P) | 0.372 | 0.441 | 0.357 | ||
| Rs6698843 | |||||
| CC | 207 (35.1) | 174 (30.9) | 172 (32.6) | ||
| CT | 266 (45.1) | 275 (48.8) | 255 (48.4) | ||
| TT | 117 (19.8) | 115 (20.3) | 100 (19.0) | 0.295 | 0.536 |
| C | 680 (57.6) | 623 (55.2) | 599 (56.8) | ||
| T | 500 (42.4) | 505 (44.8) | 455 (43.2) | 0.246 | 0.704 |
| HWE(P) | 0.062 | 0.739 | 0.751 | ||