Table 1.
The genetic association analysis between two polymorphisms of SOCS3 gene and infantile asthma susceptibility
| Genotype/allele | Case, n (%) | Control, n (%) | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| rs4969170 | GG/GA | 17 (14.29) | 46 (29.87) | 1.000 (Ref.) | - |
| AA | 102 (85.71) | 108 (70.13) | 2.556 (1.377-4.744) | 0.002 | |
| G | 19 (7.98) | 51 (16.56) | 1.000 (Ref.) | - | |
| A | 219 (92.02) | 257 (83.44) | 2.287 (1.311-3.991) | 0.003 | |
| rs4969168 | AA | 15 (12.61) | 34 (22.08) | 1.000 (Ref.) | - |
| AG | 72 (60.50) | 79 (51.30) | 2.066 (1.040-4.104) | 0.036 | |
| GG | 32 (26.89) | 41 (26.62) | 1.216 (0.547-2.702) | 0.631 | |
| AG/GG | 104 (87.39) | 120 (77.92) | 1.964 (1.013-3.808) | 0.043 | |
| A | 102 (42.86) | 147 (47.73) | 1.000 (Ref.) | - | |
| G | 136 (57.14) | 161 (52.27) | 1.217 (0.866-1.711) | 0.257 | |