Table 2.

Definition of parameters and experimental values in neutrophil immune response model.

Parameters	Description	Value	References
r pn	Rate at which pathogens are killed by neutrophils	20–100/per neutrophil/h	[41]
r t1max⁡	The maximum number of TNF-α being released by Kupffer Cells per enzyme molecule per hour	10/h	Estimated
r t2max⁡	The maximum number of TNF-α being released by activated neutrophils per enzyme molecule per hour	1000/h	Estimated
m t1	Number of Kupffer Cells at which the reaction rate is half of maximum production rate	10000 cells	Estimated
m t2	Number of activated neutrophils at which the reaction rate is half of maximum production rate	10000 cells	Estimated
k c2	Concentration of neutrophils which phagocytose half of Salmonella	1.5 × 10−4	[42]
u t	Degradation rate of TNF-α	0.025–0.5/h (measured in kidney)	[43]
k rd	Influx rate of neutrophils into blood vessel	0.1–0.72/h	[44]
N s	Resting neutrophil carrying capacity in blood vessel	3.5 × 105 cells	[22]
μ nr	Apoptotic rate of resting neutrophils per hour	0.069–0.12/h	[45]
μ n	Apoptotic rate of activated neutrophils per hour	0.05/h	[45]
k nub	Unbinding rate of activated neutrophils per hour	0.01–0.5/h	Estimated
k r1	Auxiliary parameter associated with the activation rate of resting neutrophils	3/h	Estimated
u r1	Degradation rate of parameter r 1 to maintain a slow-saturation curve	0.003/h	Estimated