Table 5.

Alcohol consumption at HUNT1 and the association with vascular dementia (VaD) including mixed VaD/VD up till 27 years later

	Hazard ratios (95 % Confidence Intervals, CI) alcohol consumption last 14 days
	Abstainers	Drinking 0 times, not abstainers	Drinking 5 or more times	Unknown
	1.89 (1.30–2.74) p = 0.001	1.29 (0.96–1.73) p = 0.091	1.63 (1.00–2.65) p = 0.050	3.06 (1.86–5.03) p < 0.001
Vascular dementia including mixed AD/VD adjusted for ageb, sex	1.24 (0.83–1.84) p = 0.298	1.01 (0.74–1.37) p = 0.951	1.52 (0.93–2.47) p = 0.095	1.76 (1.04–2.97) p = 0.033
Vascular dementia including mixed AD/VD Fully adjusted modela	1.15 (0.75–1.76) p = 0.520	0.96 (0.71–1.32) p = 0.817	1.43 (0.87–2.36) p = 0.161	1.48 (0.85–2.61) p = 0.167

HUNT1Q2-participants born between 1905 and 1946 (n = 284/N = 40,435)

Dementia group included vascular and mixed (AD/VD) dementia cases only. Other dementia cases in these analyses were censored. Reference group: Respondents reporting to drink alcohol 1-4 times the last fortnight

^aadjusted for age, ^b (ageHUNT1-45)², sex, age, education, severe hypertension (≥ 160/90), BMI ≥ 30, smoking and symptoms of depression