Table 4.
The association between TK activity and stroke recurrence.
| Stroke recurrence | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 |
|---|---|---|---|---|
| Total stroke, n | 80 | 80 | 80 | 81 |
| Events, number (%) | 42 (52.5) | 25 (31.3) | 21 (26.3) | 17 (21) |
| Unadjusted (RR)† | 1 | 0.55 (0.34–0.91) | 0.43 (0.25–0.72) | 0.32 (0.18–0.54) |
| P value | 0.019 | 0.001 | <0.001 | |
| Adjusted (RR)† | 1 | 0.59 (0.35–0.99) | 0.44 (0.25–0.78) | 0.33 (0.18–0.61) |
| P value | 0.048 | 0.005 | <0.001 | |
| Ischemic stroke | 40 | 37 | 55 | 42 |
| Events, number (%) | 22 (55) | 14 (37.8) | 15 (27.3) | 7 (16.7) |
| Unadjusted (RR)† | 1 | 0.71 (0.36–1.39) | 0.45 (0.23–0.87) | 0.25 (0.11–0.58) |
| P value | 0.321 | 0.018 | 0.001 | |
| Adjusted (RR)† | 1 | 0.90 (0.43–1.89) | 0.59 (0.28–1.22) | 0.30 (0.12–0.75) |
| P value | 0.779 | 0.155 | 0.01 | |
| Hemorrhagic stroke | 40 | 43 | 25 | 39 |
| Events, number (%) | 20 (50) | 11 (25.6) | 6 (24) | 10 (25.6) |
| Unadjusted (RR)† | 1 | 0.44 (0.21–0.92) | 0.39 (0.16–0.98) | 0.39 (0.18–0.84) |
| P value | 0.028 | 0.046 | 0.016 | |
| Adjusted (RR)† | 1 | 0.27 (0.12–0.63) | 0.16 (0.06–0.46) | 0.17 (0.07–0.46) |
| P value | 0.002 | 0.001 | <0.001 |
TK activity in quartile 1 (<1.063 Eu/mL), quartile 2 (1.063–1.667 Eu/mL), quartile 3 (1.667–1.988 Eu/mL), and quartile 4 (>1.988 Eu/mL).
TK: tissue kallikrein; RRs: relative risks. †RRs (95% confidence interval). Adjusted RRs have been adjusted for age, sex, presence or absence of hypertension, diabetes, hyperlipidemia, smoking, weight, BMI, SBP, DBP, total cholesterol, triglyceride, and HDL.