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. 2015 Sep 14;2015:814089. doi: 10.1155/2015/814089

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Copyright © 2015 Yingjie Cao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of triptolide on the subcellular localization of the Smad3 and Ski proteins of the TGF-β1-induced RMC. In control group, Smad3 protein was mainly expressed in the cytoplasm but, in the TGF-β1-induced group, the level of expression of Smad3 protein was significantly higher and was mainly localized in the nucleus. Ski protein of the control group was expressed mainly in the nucleus. The level of expression of Ski in and out of the nucleus of the TGF-β1-induced group was significantly higher and was mainly localized in the cytoplasm (bar = 75 μm).