Table 3.
Clinical and biochemical characteristics among subjects according to genotypes of R219K.
| T2DM (n = 164) | Controls (n = 165) | P value | |||||
|---|---|---|---|---|---|---|---|
| GG | GA | AA | GG | GA | AA | ||
| Age (years) | 61.94 ± 9.20 | 61.40 ± 9.98 | 66.06 ± 9.76 | 54.94 ± 11.79 | 55.38 ± 12.11 | 54.06 ± 10.98 | 0.583 |
| BMI (Kg/m²) | 27.68 ± 5.12 | 28.32 ± 5.54 | 27.29 ± 3.69 | 27.53 ± 8.86 | 27.17 ± 4.44 | 26.08 ± 4.24 | 0.767 |
| WHR | 0.95 ± 0.07 | 0.97 ± 0.25 | 0.96 ± 0.06 | 0.88 ± 0.13 | 1.02 ± 0.82 | 0.91 ± 0.06 | 0.791 |
| SBP (mm Hg) | 145.45 ± 22.85 | 134.98 ± 25.86 | 145.85 ± 24.12 | 136.72 ± 20.59 | 138.12 ± 19.44 | 139.34 ± 21.93 | 0.479 |
| DBP (mm Hg) | 78.21 ± 10.14 | 78.44 ± 15.15 | 78.28 ± 11.41 | 79 ± 11.21 | 79.36 ± 10.12 | 80.96 ± 10.43 | 0.481 |
| FPG (mmol/L) | 8.76 ± 3.66 | 8.65 ± 3.39 | 8.11 ± 3.04 | 5.62 ± 1.14 | 5.35 ± 1.24 | 5.42 ± 1.69 | 0.036* |
| HbA1c (mmol/mol) | 8.22 ± 2.14 | 7.76 ± 2.15 | 7.24 ± 2.46 | 5.92 ± 0.69 | 5.91 ± 0.63 | 6.07 ± 0.65 | 0.001* |
| LDL (mmol/L) | 2.34 ± 0.92 | 2.33 ± 0.87 | 2.46 ± 0.94 | 2.71 ± 0.95 | 2.47 ± 0.91 | 2.80 ± 1.03 | 0.138 |
| HDL (mmol/L) | 1.24 ± 0.40 | 1.27 ± 0.54 | 1.31 ± 0.69 | 1.28 ± 0.44 | 1.19 ± 0.46 | 1.10 ± 0.29 | 0.382 |
| TG (mmol/L) | 1.85 ± 1.45 | 1.58 ± 0.76 | 1.90 ± 0.82 | 1.26 ± 0.79 | 1.29 ± 0.81 | 1.25 ± 0.58 | 0.139 |
| Cholesterol (mmol/L) | 4.42 ± 1.19 | 4.29 ± 1.08 | 4.45 ± 1.11 | 4.66 ± 1.16 | 4.30 ± 1.21 | 4.34 ± 1.04 | 0.218 |
* P < 0.05.