Table 5.
Clinical and biochemical characteristics among subjects according to genotypes of R230C.
| T2DM (n = 164) | Controls (n = 165) | P value | |||||
|---|---|---|---|---|---|---|---|
| CC | CT | TT | CC | CT | TT | ||
| Age (years) | 62.19 ± 8.82 | 62.04 ± 10.03 | 62.30 ± 10.55 | 56.68 ± 10.60 | 52.80 ± 12.58 | 56.00 ± 12.00 | 0.363 |
| BMI (Kg/m²) | 28.01 ± 5.33 | 27.66 ± 5.27 | 28.00 ± 4.26 | 28.60 ± 8.05 | 26.10 ± 4.53 | 26.14 ± 4.72 | 0.096 |
| WHR | 0.94 ± 0.05 | 0.98 ± 0.22 | 0.93 ± 0.05 | 1.02 ± 0.94 | 0.92 ± 0.06 | 0.91 ± 0.08 | 0.730 |
| SBP (mm Hg) | 143.53 ± 25.25 | 140.19 ± 24.75 | 142.25 ± 20.98 | 139.28 ± 20.19 | 135.04 ± 18.38 | 140.82 ± 23.40 | 0.351 |
| DBP (mm Hg) | 78.53 ± 13.96 | 77.87 ± 11.33 | 79.10 ± 8.65 | 79.70 ± 10.50 | 78.83 ± 10.46 | 80.67 ± 10.87 | 0.615 |
| FPG (mmol/L) | 8.66 ± 3.71 | 8.88 ± 3.32 | 7.93 ± 3.49 | 5.42 ± 0.92 | 5.50 ± 1.74 | 5.42 ± 0.90 | 0.193 |
| HbA1c (mmol/mol) | 8.10 ± 2.09 | 8.02 ± 2.22 | 7.41 ± 2.38 | 5.83 ± 0.67 | 6.01 ± 0.69 | 6.00 ± 0.52 | 0.192 |
| LDL (mmol/L) | 2.58 ± 1.01 | 2.18 ± 0.78 | 2.13 ± 0.73 | 2.59 ± 0.98 | 2.72 ± 0.97 | 2.48 ± 0.87 | 0.241 |
| HDL (mmol/L) | 1.33 ± 0.51 | 1.23 ± 0.47 | 1.12 ± 0.36 | 1.18 ± 0.41 | 1.23 ± 0.34 | 1.20 ± 0.60 | 0.494 |
| TG (mmol/L) | 1.78 ± 1.08 | 1.70 ± 1.23 | 1.89 ± 1.42 | 1.29 ± 0.78 | 1.32 ± 0.83 | 1.14 ± 0.54 | 0.968 |
| Cholesterol (mmol/L) | 4.69 ± 1.22 | 4.16 ± 1.07 | 4.08 ± 0.88 | 4.40 ± 1.24 | 4.56 ± 1.09 | 4.25 ± 1.17 | 0.119 |
P value < 0.05, between T2DM and controls.