Table 2.

Distribution of PIE and Putative PIE Domains.

Genus	Strain	vCCI	CrmB	SCP-2	C8	M2	A41	SCP-3	T4	SCP-1	CrmD	COTV030	CPXV-007	SCP-like	M2-like	A41-like	ORF-CBP	SB87-113	DPXV-016	BPSV-117	ORF-GIF
Orthopoxvirus	VARV BRZ66	1	1			1	1
	VARV CNG70	1	1			1	1
	VARV GAR	1	1			1	1
	VARV GUI69	1	1			1	1
	VARV IND64	1	1			1	1
	VARV SLN68	1	1			1	1
	MPXV SL	2	2			1	1	1		1
	MPXV Z96	2	2			1	1	1	1	1
	CMLV M96	2	2		1	1	1	0	1	1
	TATV	0/0	0/0		0	1	1	1	1	1
	HPXV	2	2	0	1	1	1	1	0	1
	CPXV GRI	2	2	1	1	0	1	1	1	1	1
	CPXV BRI	2	2	1	1	1	1	1	1	1	1
	CPXV GER	2	2	1	1	1	1	1	1	1	0		1
	ECTV MOS	2	0/0	1			1	1			2
	VACV WR	0/0	0/0	0/0	1	1	1	1	0	1
Unclassified	YOKA					1			2						1
Leporipoxvirus	MYXV LAU	2	2			1			2
Yatapoxvirus	YMTV YLD					1									1
Unclassified	COTV			1		1						1		2		2
Cervidpoxvirus	DPXV W83					1			2						1				1
Caporipoxvirus	LSDV 2490								2
	SPPV A								2
	GTP G20								2
	GTP PEL								2
Parapoxvirus	BPSV																1			1
	ORF																1				1
	SB87																2	1			1
	PCPV																1				1
Ligands		Chemokines	Chemokines	Chemokines	Unknown	Unknown	CK/GAGs	Chemokines	MHC class I	Chemokines	Chemokines	Unknown	Unknown	Unknown	Unknown	Unknown	Chemokines	Unknown	Unknown	Unknown	GM-CSF, IL-2