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. 2015 Sep 16;6:200. doi: 10.3389/fphar.2015.00200

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Copyright © 2015 Pereira, Martynhak, Andreatini and Svenningsson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of saline or WAY208466 (9 mg/kg, ip) on the phosphorylation states of Ser^217/221-MEK (A), Thr^202/204-Erk1/2 (B), Ser⁸⁴⁵-GluA1 (C) and the ratio matureBDNF/proBDNF (D) in the prefrontal cortex (PFC), hippocampus, and caudate-putamen (CPu). ^∗p < 0.05; ^∗∗p < 0.01 compared to saline group. Mean ± SEM; n = 6–8 mice per group.