Table 2.
Baseline and change of biochemical and clinical variables during the study period (end of the study minus baseline) for the Responders group and Non-responders group.
| variables | Responders (n = 19) |
Non-responders (n = 8) |
p Value | ||
|---|---|---|---|---|---|
| Baseline | Change | Baseline | Change | ||
| Age | 54.0 ±7.8 | – | 56.0 ± 6.5 | – | 0.064 |
| Duration of diabetes (years) | 4. 3 ± 3.6 | – | 7.6 ± 2.7 | – | 0.042 |
| Weight (kg) | 73.4 ± 11.5 | −1.6 ± 0.3 | 76.5 ± 10.6 | −0.1 ± 0.2 | 0.011 |
| BMI (kg/m2) | 26.2 ± 6.4 | 0.1 ± 0.1 | 26.9 ± 3.1 | 0.0 ± 0.1 | 0.587 |
| FBG (mmol/L) | 7.0 ± 1.1 | −0.3 ± 0.2 | 7.4 ± 1.0 | −0.2 ± 0.1 | 0.882 |
| 2 h-BG (mmol/L) | 12.0 ± 1.2 | −2.2 ± 0.9 | 12.5 ± 1.8 | −0.7 ± 0.3 | 0.007 |
| HbA1c (%) | 7.3 ± 0.8 | −0.4 ± 0.2 | 7.7 ± 1.1 | −0.1 ± 0.1 | 0.048 |
| TG (mmol/L) | 1.5 ± 0.6 | 0.1 ± 0.2 | 1.9 ± 0.6 | 0.1 ± 0.2 | 0.330 |
| TC (mmol/L) | 4.6 ± 0.9 | −0.6 ± 0.2 | 5.0 ± 0.8 | −0.5 ± 0.4 | 0.587 |
| HDL-c (mmol/L) | 1.2 ± 0.3 | 0.1 ± 0.1 | 1.0 ± 0.3 | 0.0 ± 0.1 | 0.724 |
| LDL-c (mmol/L) | 2.7 ± 0.7 | −0.3 ± 0.3 | 3.0 ± 0.8 | −0.3 ± 0.2 | 0.936 |
| CRP (mg/L) | 1.4 ± 1.4 | −1.1 ± 0.4 | 1.8 ± 1.6 | −0.2 ± 0.3 | 0.021 |
| HOMA-IR | 4.1 ± 2.5 | −0.6 ± 0.2 | 4.9 ± 3.1 | −0.2 ± 0.4 | 0.342 |
| HOMA-β | 56.4 ± 20.2 | 10.5 ± 3.6 | 30.3 ± 24.0 | 6.4 ± 4.7 | 0.572 |
Normally distributed data expressed as mean ± SD and non-normally distributed data were log-transformed for use with parametric statistics.