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. 2015 Sep 17;9:130. doi: 10.3389/fnsys.2015.00130

Figure 1.

Figure 1

Rest (pre/post) and Delayed Nonmatch-to-Sample (DNMS) task recording paradigm. (A) Prior to each testing session, all rats were recorded in a white, rectangular plastic box for 25–30 min (pre-task recording). Upon completion of pre-task recording phase, the same rats were injected with either vehicle or delta-9-tetrahydrocannabinol (THC) 5–10 min before the start of delayed nonmatch-to-sample (DNMS) task. Immediately after completing the DNMS task, rats were put back into the same plastic chamber for another 25–30 min recording (post-task recording). (B) Progression of the DNMS task is illustrated. A 10 s Intertrial Interval (ITI) precedes the Sample Presentation (SP). Rats must make the Sample Response (SR) and remember the lever position throughout the variable 1–30 s delay that terminates after the Last Nosepoke (LNP). The LNP signals extension of both levers and rats receive a water reward (reinforcement) for appropriately making a Nonmatch Response (NR).