FIGURE 6.

Day 10 histological sections of the ileum of OlPC-treated C57BL/6 IFNγR-KO mice infected with C. parvum. Representative transverse sections of the ileum stained with H&E showing disease progression. (A) Ileum of mice treated with 20 mg/kg/day of OlPC shows significant epithelial damage and abundance of oocysts. (B) Ileum of mice treated with 30 mg/kg/day of OlPC. (C) Ileum of mice treated with 40 mg/kg/day of OlPC. Sections from (B,C) reveal mild gut epithelial damage and rare presence of oocysts. Each group is represented at 100 and 400x magnifications. Red arrows indicate C. parvum oocysts.