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. 2015 Sep 24;6:255. doi: 10.3389/fphys.2015.00255

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Copyright © 2015 Vierheller, Neubert, Falcke, Gilbert and Chamakuri.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Two examples for channel placement in the CRU model. For 30 RyRs and 8 LCCs (left) and 16 RyRs and 5 LCCs (right). The number of RyR channels per CRU obeys an exponential distribution with an average of 50 across all CRUs.