Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Withdrawal rates
RCT 4-armed trial	136 people with CFS, Oxford criteria In review	Withdrawal rates 25/68 (37%) with graded exercise therapy, with or without fluoxetine 15/69 (22%) with general advice, with or without fluoxetine	RR 1.70 95% CI 0.98 to 2.90		Not significant
RCT 4-armed trial	641 adults with CFS (Oxford criteria)	Serious adverse events 13/160 (8%) with graded exercise therapy 7/160 (4%) with specialist medical care	P = 0.0142	Effect size not calculated	specialist medical care