Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Physical functioning
RCT 4-armed trial	148 people with CFS, Oxford criteria In review	Mean short-form (SF)-36 physical functioning score (score range: 10–30, where 10 = maximum impairment and 30 = no impairment) 1 year 25.1 with minimum intervention graded exercise 16.9 with written information	P <0.001 for minimum intervention graded exercise v control	Effect size not calculated	graded exercise therapy plus education
RCT 4-armed trial	148 people with CFS, Oxford criteria In review	Mean SF-36 physical functioning score (score range: 10–30, where 10 = maximum impairment and 30 = no impairment) 1 year 24.3 with telephone intervention graded exercise 16.9 with written information	P <0.001 for telephone intervention graded exercise v control	Effect size not calculated	graded exercise therapy plus education
RCT 4-armed trial	148 people with CFS, Oxford criteria In review	Mean SF-36 physical functioning score (score range: 10–30, where 10 = maximum impairment and 30 = no impairment) 1 year 24.9 with maximum intervention graded exercise 16.9 with written information	P <0.001 for maximum intervention graded exercise v control	Effect size not calculated	graded exercise therapy plus education