Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Fatigue
RCT	107 depressed and non-depressed people with CFS (Oxford criteria) In review	Mean scores on subscale of Checklist Individual Strength 8 weeks with fluoxetine with placebo Absolute results not reported	Mean difference –0.16 95% CI –0.64 to +0.31		Not significant
4-armed trial	136 people with CFS (Oxford criteria) In review	Fatigue severity 12 weeks with fluoxetine with placebo Absolute results not reported	Reported as not significant P value not reported		Not significant