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. 2015 Oct 15;78(8):525–533. doi: 10.1016/j.biopsych.2014.09.010

Figure 2.

Figure 2

Scatter plots depicting associations between the change in serotonin reuptake transporter (SERT) binding potential (BP) and in plasma steroid hormones for (A) female-to-male (FtM) and (B) male-to-female (MtF) transsexuals. Scattered lines represent 95% confidence intervals. Positive associations between changes in SERT BP in amygdala, caudate, and putamen and testosterone plasma level increase within the first 4 weeks (4w) of treatment (baseline [BL] − 4w) were found in FtM transsexuals (upper row). Positive associations between changes in SERT BP in insula, mid-cingulate, and putamen and estradiol plasma level increase over the course of 4 months (4m) of treatment (BL − 4m) were found in FtM transsexuals (bottom row). PET, positron emission tomography.