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. 2015 Sep 18;5:14235. doi: 10.1038/srep14235

Figure 1. Impairment of special learning and memory in EAE mice in the late stage of disease.

Figure 1

(a,b) It displayed no obvious cognitive decline in the EAE mice in the early stage. (c) In the late stage, the latency to finding the hidden platform in the EAE mice was longer than in the control mice, especially in the first day. (d) On the detecting day, the percentage of the distance in the target quadrant is significantly shorter than that of controls. *Denotes statistical significance compared with controls (P < 0.05). **Denotes statistical significance compared with controls (P < 0.01).