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. 2015 Sep 21;5:13794. doi: 10.1038/srep13794

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(A) Formate-dependent PCE respiratory chain. (B) Pyruvate-dependent PCE respiratory chain, top: directly across the membrane employing quinone-reducing pyruvate dehydrogenase, bottom: cytoplasmic route of pyruvate oxidation via TCA cycle intermediates and ferredoxin. Abbreviations: Fdh, formate dehydrogenase; PoxB, pyruvate (quinone) dehydrogenase; Qdh, putative quinol dehydrogenase; PceAB, PCE reductive dehalogenase; PFOR, pyruvate:ferredoxin oxidoreductase; MQOR, malate:quinone oxidoreductase; Sdh/Frd, succinate dehydrogenase/fumarate reductase; OGFOR, 2-oxoglutarate:ferredoxin oxidoreductase; Fd, ferredoxin; ε-nuo, epsilonproteobacterial complex I; red arrows depict flow of electrons.