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. 2015 Sep 21;5:14314. doi: 10.1038/srep14314

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Human fibroblast-like synoviocytes (HFLSs) and RAW264 cells were cultured and exposed to either 10 μg/mL MWCNTs or CB for 24 h. Both HFLSs and RAW264 cells exhibited incorporation of MWCNTs and CB, with RAW264 cells showing increased incorporation per cell. Both MWCNTs and CB were observed in lysosomes of HFLSs and RAW264 cells. Blue: nucleus, Red: lysosome.