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. 2015 Sep 22;5:14118. doi: 10.1038/srep14118

Table 1. Drugs used in the iterative search using the TACS algorithm.

Drug Suggested Activity Obtained from Stock Conc. Final Conc.
Sunitinib Tyrosine kinase inhibitor39 Lc Laboratories USA 126.5 μM 3.16 μM
Rapamycin mTOR (mammalian target of rapamycin) inhibitor40 Sigma-Aldrich Sweden AB 86.4 μM 2.16 μM
Trichostatin A Histone deacetylase inhibitor41 Sigma-Aldrich Sweden AB 3.2 μM 0.08 μM
17-AAG Heat shock protein (HSP) inhibitor42 Lc Laboratories USA 40 μM 1 μM
Mitomycin Antitumour antibiotics43 Sigma-Aldrich Sweden AB 14.9 μM 0.37 μM
Afungin Antifungal substance Sigma-Aldrich Sweden AB 0.4 μM 0.01 μM

Stock solution for all drugs were prepared 40 times higher than the final concentrations that were restored when diluted with cell suspension in the wells of the experimental plate.