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. 2015 Sep 23;5:14432. doi: 10.1038/srep14432

Figure 4. Increased CD40L expression and IL-21 production by Vδ2 T cells from SLE patients.

Figure 4

(A) CD40L was primarily expressed on Vδ2low T cells. Fresh Vδ2 T cells were stained with a mAb against Vδ2 and CD40L or IL-21. The left panel compares the expression of CD40L and IL-21 between healthy adults and SLE patients. The right panel compares the expression of CD40L or IL-21 between Vδ2low T cells and Vδ2high T cells. The data were gated for Vδ2 T cells. (B) The percentage and MFI of CD40L+/IL-21+ cells among the total Vδ2 T cells freshly isolated from HC and SLE patients. *p < 0.05, **p < 0.01.