Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Sep 24;5:14427. doi: 10.1038/srep14427

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Mutations in the Cav1.2 homolog EGL-19 prolong spontaneous pump duration and reduce pump rate. (a) Original EPG recordings of wild type (wt) and egl-19 mutants (alleles are indicated) with prolonged pump duration (interval E-R spike is indicated). (b) Group data, pump durations (mean ± s.e.m.) during spontaneous pumping, of several egl-19 alleles; statistically significant differences to wt are indicated (***P < 0.001; **P < 0.01; *P < 0.05; one way ANOVA with Fisher post-hoc test). (c) Group data, spontaneous pump rate on food of selected egl-19 mutants, compared to wt (t-test with Bonferroni correction: ***P < 0.001; **P < 0.01; *P < 0.05). (d) Schematic of the EGL-19 α1 subunit of the L-type VGCC with the amino acid changes in the alleles listed in (e).