Figure 3. M1 macrophage CM reducing tumor growth in vivo.
NOD-SCID mice were subcutaneously injected with long-term macrophage-co-cultured A549 cells. M1 subtype macrophages reduced xenograft tumor volume (A) and weight (B). *P < 0.05, compared with M0 macrophages. Each group contained six mice, and the data represent means ± standard deviations.