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. 2015 Sep 25;5:14438. doi: 10.1038/srep14438

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Copyright © 2015, Macmillan Publishers Limited

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(a) Interactions between monitored proteins Fas, FADD, Casp-8, Casp-3 and XIAP estimated using STRING 9.1 database (b) Proteins interacting directly with Fas, FADD, Casp-8, Casp-3 and XIAP were estimated using STRING 9.1 database. The nodes represent the proteins while the lines indicate interactions in this 1^st order interactome. Only those proteins reported at a confidence level of 95% are considered. (c) The proteins interacting directly with the nodes of 1^st order interactome were extracted analogously to capture the 2^nd order interactome.