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. 2015 Sep 28;7(9):266–278. doi: 10.4329/wjr.v7.i9.266

Table 2.

A few characteristic features of established bio-markers

S. No Parameter Technique
DC MN FISH γ-H2AX
1 Culture time (h) 48 72 48 Not applicable
2 Scoring speed (cells/d) About 150 About 750 About 750 About 100/h
3 Type of aberrations detectable Unstable Unstable Stable/ unstable Unstable
4 Period of detection after exposure (yr) 2-3 2-3 > 30 2-3 d
5 Cell type/quality Metaphases/ good BN cells/good Metaphases/good Interphase cells/good
6 Baseline frequency 0.001 0.015 0.001 0.042
7 Sensitivity (Gy) 0.1 0.25 0.1 0.05

FISH: Fluorescence in situ hybridization; MN: Micronucleus; DC: Dicentric chromosome.