Table 2.
S. No | Parameter |
Technique |
|||
DC | MN | FISH | γ-H2AX | ||
1 | Culture time (h) | 48 | 72 | 48 | Not applicable |
2 | Scoring speed (cells/d) | About 150 | About 750 | About 750 | About 100/h |
3 | Type of aberrations detectable | Unstable | Unstable | Stable/ unstable | Unstable |
4 | Period of detection after exposure (yr) | 2-3 | 2-3 | > 30 | 2-3 d |
5 | Cell type/quality | Metaphases/ good | BN cells/good | Metaphases/good | Interphase cells/good |
6 | Baseline frequency | 0.001 | 0.015 | 0.001 | 0.042 |
7 | Sensitivity (Gy) | 0.1 | 0.25 | 0.1 | 0.05 |
FISH: Fluorescence in situ hybridization; MN: Micronucleus; DC: Dicentric chromosome.