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. 2015 Sep 28;5:14492. doi: 10.1038/srep14492

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(A) The green fluorescent membrane dye DiOC₆ is detected within the cytoplasm, as a dense signal around the nuclei of both the non-activate filopodial and petaloid phagocytes. (B) A few cells showed a growing network of vesicles (green arrows), validating a phagocytic activity in progress. (C) Representative image of the HSP70 levels of 6 control specimens, 6 specimens exposed to TiO₂NP and 1 to LPS, evaluated by immunoblotting. Contrary to LPS exposure, TiO₂NP exposure do not stimulate the activation of the HSP70-dependent stress response in the sea urchin immune cells.