Table 4.
Comparison between syndromic and aetiological diagnoses among persons screened for the Kisumu Incidence Cohort Study, Kisumu, Kenya, 2007–2008
| STI | Syndromic diagnosisa
|
Aetiological diagnosisb
|
Chi square p | Kappa coefficient (exact 95% CI) | PPV (exact 95% CI) | NPV (exact 95% CI) | ||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | |||||
| Overall | 83 | 10.6 | 272 | 34.2 | 0.0021 | 0.09 (0.03, 0.15) | 50.6 (39.4–61.8) | 67.2 (63.6–70.7) |
| Overall minus HSV-2 and syphilis | 80 | 9.5 | 42 | 5.0 | 0.0128 | 0.09 (−0.0001, 0.1764) | 11.3 (5.3, 20.3) | 95.7 (94.0, 97.0) |
| HSV-2 | 11 | 1.4 | 246 | 31.5 | 0.0425 | 0.03 (−0.0013, 0.06) | 63.6 (30.8–89.1) | 69.0 (65.6–72.2) |
| Gonorrhoea | 80 | 9.5 | 20 | 2.4 | 0.0078 | 0.09 (−0.0004, 0.17) | 7.5 (2.8–15.6) | 98.2 (97.0–99.0) |
| Chlamydia | 80 | 9.5 | 24 | 2.8 | 0.2734 | 0.03 (−0.04, 0.11) | 5.0 (1.4–12.3) | 97.4 (96.0–98.4) |
| Syphilis | 14 | 1.7 | 14 | 1.7 | 1.0000 | −0.02 (−0.02, −0.01) | 0.0 (0.0–23.2) | 98.3 (97.2–99.1) |
a
Diagnoses based on the signs and symptoms collected through CAPI.
b
Diagnoses based on laboratory testing.
PPV: positive predictive value; NPV: negative predictive value; HSV-2: herpes simplex virus type 2; CI: confidence interval; STI: sexually transmitted infection.