Table 1.
Baseline patient demographic, clinical and pathological characteristics
| UD | LD-Stable | LD-Unstable | Overall | p Value | |||||
|---|---|---|---|---|---|---|---|---|---|
| No. pts (%) | 419 | (74) | 93 | (16) | 54 | (10) | 566 | ||
| Mean/median age at operation (range) | 60/60 | (39–74) | 58/58 | (41–78) | 58/57 | (44–77) | 60/60 | (39–78) | 0.003 |
| No. operation type (%): | |||||||||
| Open | 217 | (52) | 23 | (25) | 18 | (33) | 258 | (46) | <0.001 |
| Robotic | 202 | (48) | 70 | (75) | 36 | (67) | 308 | (54) | |
| Preop PSA (ng/ml): | |||||||||
| Mean (median) | 6.4 | (5.4) | 6 | (5.4) | 7.6 | (5.6) | 6.4 | (5.4) | 0.267 |
| No. less than 4.0 (%) | 76 | (18) | 23 | (25) | 6 | (11) | 105 | (19) | 0.215 |
| No. 4.0–10.0 (%) | 304 | (72) | 63 | (68) | 40 | (74) | 407 | (72) | |
| No. greater than 10.0 (%) | 39 | (9) | 7 | (7) | 8 | (15) | 54 | (10) | |
| No. clinical stage (%): | |||||||||
| Less than T1c | 4 | (1) | 4 | (1) | 0.164 | ||||
| T1c | 265 | (65) | 48 | (53) | 36 | (69) | 349 | (63) | |
| Greater than T1c | 140 | (34) | 43 | (47) | 17 | (31) | 200 | (36) | |
| Unknown | 10 | 2 | 1 | 13 | |||||
| No. preop Gleason sum (%): | |||||||||
| Less than 7 | 283 | (69) | 65 | (70) | 24 | (46) | 372 | (68) | 0.007 |
| 7 | 106 | (26) | 25 | (27) | 23 | (43) | 154 | (27) | |
| Greater than 7 | 19 | (5) | 3 | (3) | 6 | (11) | 28 | (5) | |
| Unknown | 11 | 1 | 12 | ||||||
| No. NCCN clinical risk group (%): | |||||||||
| Low | 249 | (63) | 58 | (64) | 23 | (43) | 330 | (61) | 0.034 |
| Intermediate | 117 | (30) | 26 | (29) | 20 | (38) | 163 | (30) | |
| High | 30 | (7) | 7 | (7) | 10 | (19) | 47 | (9) | |
| Unknown | 23 | 2 | 1 | 26 | |||||
| No. pathological stage (%): | |||||||||
| pT2 | 340 | (81) | 74 | (80) | 33 | (61) | 446 | (79) | 0.022 |
| Greater than pT2 | 79 | (19) | 19 | (20) | 21 | (39) | 120 | (21) | |
| No. pathological Gleason sum (%): | |||||||||
| Less than 7 | 209 | (50) | 41 | (44) | 17 | (32) | 267 | (47) | 0.052 |
| 7 | 191 | (46) | 47 | (51) | 31 | (57) | 269 | (48) | |
| Greater than 7 | 19 | (4) | 5 | (5) | 6 | (11) | 30 | (5) | |
| No. surgical margins (%): | |||||||||
| Neg | 359 | (86) | 79 | (85) | 38 | (70) | 476 | (84) | 0.021 |
| Pos | 59 | (14) | 14 | (15) | 16 | (30) | 89 | (16) | |
| Unknown | 1 | 1 | |||||||
| Median mos followup (range) | 85 | (38–224) | 69 | (45–183) | 84 | (48–218) | 82 | (38–224) | <0.001 |