Table 3.

Univariate and multivariate BCR models

	HR (95% CI)		p Value
Univariate
PSA group:
UD vs LD-unstable	18.14	(11.36–28.97)	<0.001
UD vs LD-stable	1.63	(0.78–3.41)
Pretreatment PSA (ng/ml):
Less than 4 vs 4–10	1.69	(0.84–3.40)	0.162
Less than 4 vs greater than 10	2.29	(0.98–5.36)
Clinical Gleason sum:
Less than 7 vs 7	2.02	(1.26–3.21)	<0.001
Less than 7 vs 8–10	4.06	(1.97–8.35)
cT:
Less than T1c vs T1c	0.50	(0.07–3.60)	0.652
Less than T1c vs greater than T1c	0.58	(0.08–4.25)
NCCN clinical risk group:
Low vs intermediate	1.62	(0.96–2.63)	<0.001
Low vs high	3.50	(1.86–6.60)
Surgery type (open vs robotic)	1.12	(0.66–1.89)	0.672
pT (pT2 vs greater than pT2)	2.72	(1.75–4.20)	<0.001
Pathological Gleason sum:
Less than 7 vs 7	2.29	(1.40–3.74)	<0.001
Less than 7 vs 8–10	4.75	(2.32–9.72)
Surgical margin status (neg vs pos)	2.36	(1.49–3.78)	<0.001
Multivariate
PSA group:*
UD vs LD-unstable	15.97	(9.85–25.9)	<0.001
UD vs LD-stable	1.65	(0.79–3.45)
pT (pT2 vs greater than pT2)	1.76	(1.13–2.76)	0.013
Pathological Gleason sum:
Less than 7 vs 7	2.32	(1.39–3.85)	<0.001
Less than 7 vs 8–10	3.37	(1.62–7.03)
Surgical margin status (neg vs pos)	1.76	(1.1–2.81)	0.019

^*Concordance index 0.827 (95% CI 0.778–0.887).