Table 3. Alteration of genes involved in oxidative damage and ROS metabolism in the cochlea of Cmah-null mice.

Subsets	Groups	Genes
Antioxidants	Glutathion Peroxidases (Gpxs)	Gpx1 (−45.63), Gpx2 (−4.04), Gpx7 (−5.55)
	Peroxiredoxins(Tpxs)	Prdx1 (−24.50), Prdx4 (−107.49)
	Peroxidases	Cat (−5.59), Duox1 (−22.85), Epx (−43.83), Lpo (−158.02), Mpo (−5.61), Ptgs2 (−68.74), Rag2 (−101.27), Serpinb1b (−88.65), Tpo (−1114.36)
	Antioxidants	Alb(−3650.81), Sod1(−31.69), Srxn1(−4.20), Txnrd2(−37.61), Txnrd3(−37.40)
ROS metabolism	Superoxide Dismutases (Sod)	Sod1(−31.69), Sod2(−53.56)
	Genes involved in superoxide metabolism	Cygb (−4.12), Ncf1 (−15.17), Ncf2 (−26.17), Nos2 (−216.32), Nox1 (−685.97), Nox4 (−59.26), Noxa1 (−3891.20), Recql4 (−42.05), Scd1 (−8.50)
	Genes involved in ROS metabolism	Fmo2 (−5.95)
	Oxidative Damage Responsive Genes	Als2 (−10.64), Apoe (12.54), Cat (−5.59), Ccl5 (−51.16), Duox1 (−22.85), Epx (−43.83), Ercc2 (−9.90), Ercc6 (−9.77), Duox1 (−55.87), Gclc (−18.80), Gpx1 (−45.63), Gpx2 (−4.04), Gpx7 (−5.55), Hmox1 (−19.82), Hspa1a (−22.78), Krt1 (−5.23), Mpo (−5.61), Nqo1 (−7.81), Prdx1 (−24.50), Psmb5 (−7.16), Sod1 (−31.69), Tpo (−1114.36), Txn1 (−99.46), Txnrd2 (−37.61), Ucp3 (−41.41), Xpa (−19.89)
Oxygen Transporters		Atr (−9.36), Cygb (−4.12), Dnm2 (−6.47), Fancc (−10.66), Ift172 (−4.69), Mb (−14.77), Ngb (−257.96)