Table 2. Quantitative and case-control association result of top SNPs in UGT1A1 for total serum bilirubin levels in pediatric and adult subgroups.
Sample size | CHR | SNP | Position * | Beta | p value † | |
Pediatrics | 1067 | 2 | rs887829-T | 234668570 | 0.177 | 8.26E-47 |
Adult | 2227 | 2 | rs887829-T | 234668570 | 0.147 | 2.00E-63 |
Total | 3294 | 2 | rs887829-T | 234668570 | 0.157 | 1.30E-118 |
tail-pheno | Case/Control | OR | p value ‡ | |||
Decile | 354/370 | 2 | rs887829-T | 234668570 | 6.347 (5.02–8.01) | 8.76E-59 |
*Map Position: NCBI build 37.
†linear regression association test.
‡Chi-square test.