Table 3. Other effects associated with total serum bilirubin at FDR<0.05.
CHR | Gene | SNP | BP | Minor allele* | BETA | P value | P value- Adjusted for rs887829 | P value- Interaction with rs887829 | REF |
---|---|---|---|---|---|---|---|---|---|
8 | TDRP | rs17665859 | 445601 | C | 0.037 | 0.003 | 0.009 | 0.28 | 17 |
12 | SLCO1B3 | rs10841661 | 20984832 | T | 0.025 | 0.0003 | 0.0006 | 0.24 | 20 |
12 | SLCO1B3 | rs17680137 | 21015906 | G | 0.029 | 0.001 | 0.0013 | 0.75 | 20 |
12 | SLCO1B1 | rs4149056 | 21331549 | C | 0.032 | 0.0004 | 0.00009 | 0.21 | 16 |
20 | ZMYND8 | rs7262634 | 45834279 | C | 0.042 | 0.005 | 0.0192 | 0.2 | 24 |
Conditional P values adjusted for lead SNP in UGT1A1 (rs887829) as well as pairwise SNPxSNP interactions with (rs887829) are shown.
*All effects are for minor alleles.