Table 7.

Surveillance, Epidemiology, and End Results (SEER) Cancer Incidence Rate Trends With Joinpoint Analyses From 1992 to 2008 for the Cancers Associated With Excess Weight and Lack of Sufficient Physical Activity, by Sex, for All Racial and Ethnic Groups Combined^a

	Joinpoint Analyses (1992–2008)b
	Trend 1		Trend 2		Trend 3		Trend 4		AAPCc
Sex/Cancer Site or Typed	Years	APCe	Years	APCe	Years	APCe	Years	APCe	1999–2008	2004–2008
Both sexes
Adenocarcinoma of esophagus	1992–1999	5.4f	1999–2008	1.2					1.2	1.2
(Delay-adjusted)	1992–1999	5.4f	1999–2008	1.3					1.3	1.3
Colon and rectum	1992–1995	−2.1f	1995–1998	1.7	1998–2008	−2.4f			−2.4g	−2.4g
(Delay-adjusted)	1992–1995	−2.1f	1995–1998	1.7	1998–2008	−2.3f			−2.3g	−2.3g
Colon	1992–1995	−2.1f	1995–1998	1.5	1998–2008	−2.4f			−2.4g	−2.4g
(Delay-adjusted)	1992–1995	−2.1f	1995–1998	1.5	1998–2008	−2.3f			−2.3g	−2.3g
Pancreas	1992–2000	−0.1	2000–2008	1.1f					0.9g	1.1g
(Delay-adjusted)	1992–2001	0.0	2001–2008	1.5f					1.2g	1.5g
Kidney and renal pelvis	1992–1999	1.4f	1999–2008	3.0f					3.0g	3.0g
(Delay-adjusted)	1992–1997	1.1f	1997–2005	2.6f	2005–2008	4.4f			3.2g	3.9g
Men
Adenocarcinoma of esophagus	1992–2008	2.5f							2.5g	2.5g
(Delay-adjusted)	1992–2008	2.6f							2.6g	2.6g
Colon and rectum	1992–1995	−2.6f	1995–1998	1.5	1998–2008	−2.7f			−2.7g	−2.7g
(Delay-adjusted)	1992–1995	−2.6f	1995–1998	1.5	1998–2008	−2.6f			−2.6g	−2.6g
Colon	1992–1995	−2.9f	1995–1998	1.5	1998–2008	−2.8f			−2.8g	−2.8g
(Delay-adjusted)	1992–1995	−2.9f	1995–1998	1.4	1998–2008	−2.7f			−2.7g	−2.7g
Pancreas	1992–2002	0.0	2002–2008	1.4f					0.9g	1.4g
(Delay-adjusted)	1992–2002	0.0	2002–2008	1.8f					1.2g	1.8g
Kidney and renal pelvis	1992–2008	2.2f							2.2g	2.2g
(Delay-adjusted)	1992–2006	2.0f	2006–2008	6.2f					2.9g	4.1g
Women
Adenocarcinoma of esophagus	1992–2008	3.2f							3.2g	3.2g
(Delay-adjusted)	1992–2008	3.3f							3.3g	3.3g
Colon and rectum	1992–1995	−1.9f	1995–1998	1.9	1998–2008	−2.1f			−2.1g	−2.1g
(Delay-adjusted)	1992–1995	−1.8f	1995–1998	1.9	1998–2008	−2.0f			−2.0g	−2.0g
Colon	1992–2000	−0.2	2000–2008	−2.3f					−2.0g	−2.3g
(Delay-adjusted)	1992–2000	−0.2	2000–2008	−2.2f					−1.9g	−2.2g
Pancreas	1992–2008	0.5f							0.5g	0.5g
(Delay-adjusted)	1992–2000	−0.1	2000–2008	1.4f					1.2g	1.4g
Kidney and renal pelvis	1992–1998	1.2	1998–2008	3.1f					3.1g	3.1g
(Delay-adjusted)	1992–1998	1.1	1998–2008	3.3f					3.3g	3.3g
Breast (aged ≥50 y)	1992–1999	1.7f	1999–2004	−2.9f	2004–2008	0.0			−1.6g	0.0
(Delay-adjusted)	1992–1999	1.6f	1999–2005	−2.6f	2005–2008	1.0			−1.4g	0.1
Corpus and uterus, NOS	1992–2006	−0.2	2006–2008	2.3					0.4	1.1
(Delay-adjusted)	1992–2006	−0.2	2006–2008	2.7					0.5	1.2

Abbreviations: AAPC indicates average annual percent change; APC, annual percent change; NOS, not otherwise specified.

^aSource: SEER 13 areas covering about 14% of the US population (Connecticut, Hawaii, Iowa, Utah, and New Mexico, the Alaska Native Tumor Registry, rural Georgia and the metropolitan areas of San Francisco, Los Angeles, San Jose-Monterey, Detroit, Atlanta, and Seattle-Puget Sound).

^bJoinpoint analyses with up to 3 joinpoints yielding up to 4 trend segments (Trends 1–4) were based on rates per 100,000 persons and were age-adjusted to the 2000 US standard population (19 age groups: ages <1 year, 1–4 years, 5–9 years, …, 80–84 years, ≥85 years; Census publication p25-1130; US Bureau of the Census, Current Population Reports, p25-1130. Washington, DC: US Government Printing Office, 2000). For joinpoint analysis, the Joinpoint Regression Program was used (version 3.5, April 2011; Surveillance Research Program, National Cancer Institute, Bethesda, Md).

^cThe AAPC is a weighted average of the APCs calculated by joinpoint regression.

^dCancers are sorted according to International Classification of Diseases for Oncology Third Edition code. Adenocarcinoma of the esophagus is restricted to esophageal cancers with microscopically confirmed histology codes in the range from 8140 to 8575. Myelodysplastic syndromes are excluded from cancer-specific analyses.

^eThe APC is based on rates that were age-adjusted to the 2000 US standard population (19 age groups: <1, 1–4, 5–9, …, 80–84, ≥85 years; Census publication p25-1130).

^fThe APC is statistically significantly different from zero (2-sided t test; P <.05).

^gThe AAPC is statistically significantly different from zero (2-sided Z test; P <.05).