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. 2015 Aug 19;6(3):521–535. doi: 10.4338/ACI-2015-02-RA-0019

Table 5.

Sensitivity and specificity of additional CC groupings tested during refinement phase of the trial (Phase 6).

Site 1 Site 2 Site 3
Sensitivity Specificity PPV Sensitivity Specificity PPV Sensitivity Specificity PPV
Initial CC grouping without null 87.9% 86.8% 27.5% Not completed 91.2% 91.9% 32.9%
Refined grouping with highest specificity (with associated sensitivity)* 43.5% 96.1% 37.6% 75.6% 95.8% 54.3% 75.8% 97.2% 58.9%
Refined grouping with highest specificity with sensitivity at least 90% 91.8% 85.9% 26.1% 90.4% 92.6% 45.7% 90.0% 95.8% 52.8%

*Of the combinations tested. Clinically-relevant combinations of CCs were created in order to improve specificity while main taining a high sensitivity.

CC: chief complaint