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. Author manuscript; available in PMC: 2015 Sep 29.
Published in final edited form as: Exp Neurol. 2015 May 7;271:53–71. doi: 10.1016/j.expneurol.2015.04.023

Fig. 1.

Fig. 1

Blast cannon model adapted for spinal cord injury. A, B) An anesthetized mouse, with its back shaved, is taped in an outstretched position to a strip of foam attached to a stiff platform made of posterboard. C) The mouse holder is a transparent PVC pipe with a 2 cm circular opening. After the mouse, taped to the platform, is slid into the mouse holder, the T9 segment is centered within the circular opening. D) A plastic sheet, with a 3 mm wide × 5.5 mm long open slit, is centered over the circular opening using rubber bands (purple), in order to restrict the blast to ~3 segments (T8–10) of the vertebral column. E) Top view of the horizontally-mounted paintball gun used to deliver high-pressure air blasts. The mouse holder is shown closely apposed to the gun barrel. F) A close-up view of E, now with a mouse in the holder. Mouse nose is to the left; its dorsum faces the gun barrel.