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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Cell Physiol. 2016 Jan;231(1):31–35. doi: 10.1002/jcp.25062

Figure 2.

Figure 2

An example Hi-C heatmap depicting the types of data generated by 3C or 3C-based methods. 3C queries interactions on a one-by-one basis; 4C identifies interactions between a single region and the rest of the genome; 5C generates a high-resolution interaction matrix of a large genomic region; Capture Hi-C, ChIA-PET and other ChIP-based methods characterize chromatin-looping interactions over several different loci; and finally Hi-C queries genome-wide chromatin interactions at low or high resolution.