Table 2.
Metabolic pathways detected in brick and wood samples.
| No. | Metabolic pathway | Brick* | Wood B124* |
|---|---|---|---|
| 1 | Alanine, aspartate, glutamate metabolism | 7/39 (5 ↑) | |
| 2 | Alpha-linolenic acid metabolism | 8/24 (7 ↑) | |
| 3 | Arachidonic acid metabolism | 10/74 (10 ↑) | |
| 4 | Arginine and proline metabolism | 13/80 (13 ↑) | 9/80 (6 ↑) |
| 5 | Benzoate degradation | 5/23 (4 ↑) | |
| 6 | Biosynthesis of type II polyketide products | 9/86 (6 ↑) | |
| 7 | Biosynthesis of unsaturated fatty acids | 7/49 (5 ↑) | 6/49 (6 ↓) |
| 8 | Carotenoid biosynthesis | 5/91 (5 ↑) | |
| 9 | Diterpenoid biosynthesis | 11/69 (8 ↑) | 20/69 (12 ↑) |
| 10 | Flavonoid biosynthesis | 11/68 (11 ↑) | |
| 11 | Glucosinolate biosynthesis | 7/72 (5 ↑) | |
| 12 | Isoquinoline alkaloid biosynthesis | 7/93 (6 ↑) | 12/93 (3 ↑) |
| 13 | Nicotinate and nicotinamide metabolism | 8/46 (6 ↑) | |
| 14 | Phenyloalanine metabolism | 19/64 (16 ↑) | 10/64 (4 ↑) |
| 15 | Phenyloalanine, tyrosine, tryptophan biosynthesis | 6/31 (6 ↑) | |
| 16 | Phenylpropanoid biosynthesis | 11/51 (9 ↑) | 12/51 (7 ↑) |
| 17 | Steroid biosynthesis | 7/99 (5 ↑) | 8/45 (4 ↑) |
| 18 | Tropane, piperidine, and pyridine alkaloid biosynthesis | 9/61 (8 ↑) | |
| 19 | Tryptophan metabolism | 21/80 (20 ↑) | |
| 20 | Tyrosine metabolism | 17/75 (16 ↑) | 21/75 (8 ↑) |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis | 10/36 (9 ↑) | 11/36 (8 ↑) |
| 22 | Valine, leucine, isoleucine biosynthesis | 5/23 (5 ↑) |
The number of metabolites participating in the metabolic pathway is indicated on the right hand side of the slash, and the number of these that were (putatively) detected is indicated on the left hand side.
The number within parenthesis indicates the number of metabolites that were detected with at least a two-fold higher (↑) or a two-fold lower (↓) abundance in the activated sample as compared to the non-activated sample. A p-value of 0.01 was used to determine if a two-fold change was statistically significant or not. A metabolite is considered “detected” in a sample, if its relative abundance is at least 0.1%. The pathways are classified as follows: 
pathways typical for active primary metabolism of aminoacids, vitamins, glycerophospholipids, sulfur and nitrogen; 
pathways typical for active primary metabolism of organic acids including fatty acids and steroids; 
secondary metabolism pathways; 
pathways typical for active primary metabolism of dyes and aromatic compounds; 
pathways typical for active primary metabolism of phototrophs (CO2 assimilation, chlorophyll degradation); 
pathways involved in degradation of compounds which may originate from herbicides, insecticides, biocides and other compounds used to preserve historic materials. Downregulated pathway are represented in bold.