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. 2015 Sep 29;5:14362. doi: 10.1038/srep14362

Figure 5. The expression of inflammatory cytokines in response to Ang II with or without the presence of MAPK and NF-κB inhibitors.

Figure 5

mRNA expression of IL-8, MCP-1 and IL-6 was measured by real-time PCR 48 hours after stimulation by 10−6 M Ang II with or without the presence of the p38 MAPK inhibitor SB203580 (A) ERK1/2 inhibitor PD98059 (B) JNK inhibitor SP600125 (C) and NF-κB inhibitor BAY11-7082 (D) all at a final concentration of 10 μM. (E) The protein expression levels of IL-8, MCP-1 and IL-6 were measured by ELISA 48 hours after stimulation by 10−6 M Ang II with or without the presence of the p38 MAPK inhibitor SB203580, ERK1/2 inhibitor PD98059, JNK inhibitor SP600125 and NF-κB inhibitor BAY11-7082, all at a final concentration of 10 μM. The data were shown as mean ± SEM (*p < 0.05, **p < 0.01, ***p < 0.001, n = 4–6).