Table 4.

SNPs associated to virulence.

Tohama Reference Genome NC_02929 Position	AN in theRef.	Tohama ptxP1	CIP1672 (FHA-) ptxP1	FR4624 (FHA-/PRN-) ptxP3	FR4684 (PRN-) ptxP1	FR4929 ptxP21	FR5133 ptxP3	FR518 (PRN-) ptxP3	SNP Observed	SNP Type	Gene or Promoter Localisation	Nucleic Acid Change within Codon	AminoAcid Change
3988168	G	G	G	A	G	A	A	A	A	intergenic	ptxp
3988244	G	G	G	G	G	A	G	G	A	intergenic	ptxp
3988941	G	G	A	A	G	A	A	A	A	non synonymous	ptxA	atG/atA	M/I
3989239	G	G	A	A	A	A	A	A	A	non synonymous	ptxB	Ggc/Agc	G/S
3991376	C	C	C	T	C	T	T	T	T	synonymous	ptxC	tgC/tgT
1098920	*	*	*	*	*	C	C	C	INS (C)	frameshift	prn	ggt/gCgt	G/A
1098922	G	G	G	G	G	T	T	T	T	non synonymous	prn	Gcg/Tcg	A/S
1098926	T	T	T	T	T	*	*	*	DEL (T)	frameshift	prn
1098918	T	T	T	T	T	C	C	C	C	synonymous	prn	ggT/ggC
1176534	*	G	G	G	*	G	G	G	INS (G)	intergenic	pfim2
1176535	*	G	G	G	*	G	G	G	INS (G)	intergenic	pfim2
1176536	*	G	G	G	*	G	G	G	INS (G)	intergenic	pfim2
1176541	*	G	G	G	G	*	G	*	INS (G)	intergenic	pfim2
1176542	*	G	G	G	G	*	*	*	INS (G)	intergenic	pfim2
1176543	*	G	G	G	G	*	*	*	INS (G)	intergenic	pfim2
1176544	*	G	G	G	G	*	*	*	INS (G)	intergenic	pfim2
1176545	*	G	G	G	G	*	*	*	INS (G)	intergenic	pfim2
1176546	*	A	A	A	A	*	*	*	INS (A)	intergenic	pfim2
1626880	G	G	G	G	G	C	C	C	C	intergenic	pfim2
1637246	C	C	C	C	T	C	C	C	T	intergenic	pfim2
1647861	C	C	C	A	C	A	A	C	A	non synonymous	fim3	gCg/gAg	A/E
1984103	T	T	C	C	C	C	C	C	C	non synonymous	fimD	tTc/tCc	F/S
1965604	T	T	C	C	C	C	C	C	C	non synonymous	bvgS	Aag/Gag	K/E
1968699	G	G	G	A	G	G	G	G	A	intergenic	pfhaB
2826237	G	G	G	G	G	A	A	G	A	non synonymous	fhaS	Cac/Tac	H/Y
223961	G	G	G	G	G	G	G	A	A	non synonymous	sphB1	Gta/Ata	V/I
224066	G	G	G	G	G	A	A	G	A	non synonymous	sphB1	Gcc/Acc	A/T
511992	A	A	A	G	A	G	G	G	G	intergenic	pbteA
514171	G	G	G	A	G	A	A	A	A	intergenic	pbteA
2374322	T	T	T	C	T	C	C	C	C	non synonymous	bscI	tAc/tGc	Y/C
2376650	G	G	G	A	G	A	A	A	A	non synonymous	bopB	Ccc/Tcc	P/S
2363842	C	C	C	C	T	C	C	C	T	synonymous	bscC	ctG/ctA

* corresponds insertions or deletions.