Table 2.
Pooled estimates of effect size for the results of olive oil interventions compared to respective controls.
| Outcome Parameter | Mean Difference | 95% Confidence Interval | p-Value | No. of Studies | Sample Size | I2 (%) |
|---|---|---|---|---|---|---|
| C-reactive protein (mg/L) | −0.64 | (−0.96, −0.31) | 0.0001 | 15 | 1272 | 66 |
| Adiponectin (mg/L) | 0.44 | (−0.20, 1.09) | 0.18 | 6 | 313 | 56 |
| Interleukin-6 (pg/mL) | −0.29 | (−0.57, −0.02) | 0.04 | 7 | 857 | 62 |
| Tumor necrosis factor-α (µg/L) | 0.02 | (−0.02, 0.07) | 0.36 | 5 | 303 | 95 |
| sE-Selectin (ng/mL) | −3.16 | (−4.07, −2.25) | 0.00001 | 2 | 187 | 0 |
| sP-Selectin (ng/mL) | 10.78 | (4.01, 17.54) | 0.002 | 4 | 358 | 41 |
| sICAM-1 (ng/L) | −0.02 | (−0.04, 0.00) | 0.02 | 7 | 724 | 84 |
| sVCAM-1 (ng/L) | −0.02 | (−0.05, 0.01) | 0.14 | 8 | 524 | 37 |
| FMD (%) | 0.76 | (0.27, 1.24) | 0.002 | 8 | 851 | 26 |
FMD = flow-mediated dilatation; I2 = inconsistency (heterogeneity); ICAM-1 = Intercellular adhesion molecule-1; VCAM-1 = Vascular cell adhesion molecule-1.Markers of endothelial function.