Figure 2.

Low Ca²⁺ exposure affects the photoresponse amplitudes dramatically in WT, but not in GCAP^−/−, mice. Saturated rod responses recorded before and at different times during low Ca²⁺ exposure in representative isolated WT (A) and GCAP^−/− (B) mouse retinas. Timing of the change to low Ca²⁺ solution and flashes are indicated by arrows together with the time (in seconds) from the first flash given just before the low Ca²⁺ exposure. Responses have been normalized to the amplitude in normal Ca²⁺ solution before the solution exchange.