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. 2015 Sep 29;5:14554. doi: 10.1038/srep14554

Figure 1. Tumour Cell Survival.

Figure 1

Cell survival assay. (a) E.coli at different cfu/ml were co-incubated with AQ4N (10 μM) after which the supernatant was applied directly to LLC cells (P < 0.01). (b) E. coli at different cfu/ml were co-incubated with gemcitabine (10 μM) after which the supernatant was directly applied to 4T1 Luc cells (P < 0.01). E.coli was co-incubated with Tegafur (c) or CB1954 (d) at the indicated concentrations after which the supernatant was directly applied to TRAMPC1 cells or CT26 (P < 0.01). Data (a–f) represent the average and standard error of four technical replicates. Data shown are representative of 3 independent experiments. (e) Tumour cell survival assay stained with MTS. Gemcitabine (10 μM) was incubated with live or heat killed E. coli (P < 0.001). (f) Tumour cell survival assay. Gemcitabine (10 μM) was incubated with either bacterial lysate (equivalent amounts to cell survival assay live bacteria dosages) alone or bacterial lysate that has been heat inactivated (P < 0.001). Data represent the average and standard error of four technical replicates. Data shown are representative of 2 independent experiments.