Figure 2. HPLC analysis of drug biotransformations.
Chromatograms: (a) Top; Vehicle alone (PBS DMSO 0.1%), Bottom; E. coli alone (b) Top; Gemcitabine, Bottom; Gemcitabine and E. coli. (c) Top; Fludarabine, Bottom; Fludarabine and E. coli (d) Top; Cladribine, Bottom; E. coli and Fludarabine. (e) Top; CB1954, Bottom; E. coli and CB1954 The drugs and their derivatives were detected by UV absorbance at 254 nm.
