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. 2015 Sep 29;5:14554. doi: 10.1038/srep14554

Figure 5. E. coli increases the cytotoxicity of CB1954.

Figure 5

Subcutaneous flank CT26 tumours growing in Balb/c mice were injected i.t with bacteria or PBS vehicle alone. CB1954 (20 mg/kg) was injected i.p. for the duration of the experiment at 3 day intervals. (a) Tumour volume (%) relative to the first day of CB1954 injection (day 0) is shown. (b) Kaplan-Meier plots showing mouse survival over time. The median survival post Day 0 of the CB1954 + bacteria group was significantly greater than that of the CB1954 alone group (26 days vs. 8 days. P = 0.0374). Data are expressed as mean ± SEM of 3-5 individual mice per group.