Table 1. Summary of observations from in vitro cytotoxicity screen of drugs with bacteria using the bacterial cell kill assay. n/d = not determined, NC = No Change.

Drug Name	Drug Class	Cytotoxicity
		E. coli	L. welshimeri
Tegafur	Anti-metabolite	Up	NC
Fludarabine de phosphate	Anti-metabolite	Up	Up
Capecitabine	Anti-metabolite	NC	NC
5-fluorocytosine	Anti-metabolite	Up	NC
5-fluorouracil	Anti-metabolite	NC	NC
6-Mercaptopurine-2′-deoxyriboside	Anti-metabolite	Up	n/d
Pentostatin	Anti-metabolite	NC	NC
Cytarabine	Anti-metabolite	NC	NC
Clofarabine	Anti-metabolite	NC	NC
Cladribine	Anti-metabolite	Down	Down
Valacyclovir	Anti-metabolite	NC	n/d
Ara G hydrate	Anti-metabolite	NC	NC
Nelarabine	Anti-metabolite	NC	NC
Vidarabine	Anti-metabolite	Down	NC
Gemcitabine	Anti-metabolite	Down	NC
Doxorubicin	Anti-tumour Antibiotics	Down	n/d
Daunorubicin	Anti-tumour Antibiotics	Down	Down
Vinblastine	Anti-tumour Antibiotics	NC	n/d
Actinomycin	Anti-tumour Antibiotics	NC	n/d
Idarubicin	Anti-tumour Antibiotics	Down	n/d
Mitomycin C	Anti-tumour Antibiotics	NC	n/d
Streptonegrin	Anti-tumour Antibiotics	NC	n/d
Etoposide phosphate	Topo Isomerase Inhibitor	Down	NC
Irinotecan	Topo Isomerase Inhibitor	NC	NC
AQ4N	Topo Isomerase Inhibitor	Up	n/d
Mitoxantrone	Topo Isomerase Inhibitor	Down	n/d
Β-Lapachone	Topo Isomerase Inhibitor	Down	n/d
Estramustine	Alkylating Agent	NC	n/d
CB1954	Alkylating Agent	Up	Up
Menadione	Reactive oxygen generator	Down	n/d