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Palmitoyl acyltransferase DHHC21 mediates activation of the Fas signaling pathway. (A) Activation of the Fas signaling pathway in Jurkat cells stimulated with Fas ligand in cells transduced with DHHC21-specific (shDHHC21) or control (shControl) shRNA. (B) Fas-dependent calcium release in Jurkat cells expressing DHHC21-specific (shDHHC21) or control (shControl) shRNA. Shown are single-cell responses representative of hundreds of determinations.
