Table 2.

Summary of AMA1 genetic data

Region	N	S	dN	dS	k	π Jukes Cantor	H	Hd	H†	Tajima's D	Fu and Li's D*	Fu and Li's F*
All	56	13 (13)	10	3	4.041	0.0032	8	0.771	—	1.259	1.513**	1.688**
Asia	7	12 (12)	9	3	6	0.00475	4	0.857	2	1.225	1.573‡	1.642**
Egypt/Libya	7	3 (3)	0	3	1.714	0.00135	2	0.571	0	1.811	1.297	1.522
Europe/United States	6	4 (4)	1	3	2.4	0.00189	3	0.8	0	1.640	1.641	1.670
Nigeria	31	11 (3)	8	3	4.275	0.00338	4	0.546	2	1.766	1.440**	1.805**
Venezuela	5	2 (2)	0	2	1.2	0.00095	2	0.6	0	1.459	1.459	1.432

All analyses were restricted to the signal peptide cleaved EtAMA1 ectodomain. Tajima’s D and Fu and Li’s D* and F* tests were used to assess of the extent or neutrality of signatures of selection with significance: **P < 0.05; ^‡P < 0.02. All measures were calculated using DnaSP v5.10.01. dN, the number of nonsynonymous variant sites; dS, the number of synonymous variant sites; H, the number of sequence haplotypes detected; H^†, the number of haplotypes specific to a region; Hd, the haplotype diversity; k, the average number of pairwise differences; N, the number of sequences tested; π, nucleotide diversity, calculated with the Jukes Cantor correction; S, the number of variant sites detected, with the number of parsimony-informative variant sites shown in parentheses.